• to be a nuisance to sy, to be trying, to drive sy round the bend, to fray sy's nerves, to get in one's hair, to get on sy's nerves, to get on sy's works, to get under sy's skin, to give sy the worms, to grate on sy's nerves, to jar on sy's nerves, to set sy on edge, to set sy's nerves on edge
• he can't endure that brat
• to make oneself a nuisance to one's neighbours